CCR9 ligand-Linker Conjugate 1
CCR9 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate containing a CCR9 ligand and a PROTAC linker, which recruits E3 ligases. USP7 Ligand-Linker Conjugates 1 can be used to synthesize PROTAC CCR9 Degrader 1 (HY-181287).
For research use only. We do not sell to patients.
- CAS No.: 2906191-39-5
- Formula: C28H32ClN5O7S
- Molecular Weight:618.10
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
CCR9 |
Chemical Information
-
CAS No. 2906191-39-5
-
Molecular Weight 618.10
-
Formula C28H32ClN5O7S
-
SMILES
O=C(C1=CC(Cl)=CC=C1NS(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C3=CC(OCCOCCOCCN=[N+]=[N-])=[N+]([O-])C=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Huber ME, et al. A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands, New Drug Leads and PROTACs. Angew Chem Int Ed Engl. 2022;61(12):e202116782. [Content Brief]
[2]. Frost A, et al. Allosteric PROTACs: Expanding the Horizon of Targeted Protein Degradation. J Am Chem Soc. 2026;148(3):2823-2837. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)