TMEM18 - transmembrane protein 18 Gene

Also Known as lncND

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 129787

About TMEM18

Cytogenetic location: 2p25.3 Genomic coordinates (GRCh38): 2:663,877-677,406 (from NCBI)

This gene has 8 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in ovary (RPKM 18.2), thyroid (RPKM 13.8) and 25 other tissues.

Summary

Predicted to enable DNA binding activity. Involved in cell migration. Located in nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM18 Products (3)

mRNA Protein Name
NM_001352680.2 NP_001339609.1 transmembrane protein 18 isoform 2
NM_001352681.1 NP_001339610.1 transmembrane protein 18 isoform 3
NM_152834.4 NP_690047.2 transmembrane protein 18 isoform 1

TMEM18 Protein Structure

TMEM18

TMEM18: Transmembrane protein 18 (13 - 133)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

transmembrane protein 18

Related Diseases

Diseases Alias
Meier-Gorlin Syndrome 4

  • MGORS4

  • Meier-Gorlin Syndrome, Type 4
Leptin Deficiency Or Dysfunction

  • Morbid Obesity

  • Obesity Due To Congenital Leptin Deficiency

  • LEPD

  • Congenital Leptin Deficiency

  • Obesity, Morbid

  • Obesity, Morbid, Due To Leptin Deficiency

  • Severe Obesity

  • Obesity, Morbid, Nonsyndromic 1

  • Leptin Deficiency

  • Obesity, Severe, Due To Leptin Deficiency

  • Leptin

  • Morbid Obesity Due To Leptin Deficiency

  • Obesity Morbid

  • Leptin Dysfunction
Body Mass Index Quantitative Trait Locus 11

  • OBESITY

  • Obesity, Susceptibility To

  • Leanness, Inherited

  • Obesity, Susceptibility To, Bmiq11

  • Obesity, Mild, Early-Onset

  • Obesity, Association With

  • Obesity, Early-Onset, Susceptibility To

  • Obesity, Severe

  • Obesity, Severe, And Type Ii Diabetes

  • Obesity, Late-Onset

  • Obesity , Susceptibility To

  • BMIQ11

  • Obesity Bmiq11

  • Obesity, Early-Onset

  • Simple Obesity Nos

  • Excess Fat

  • Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

  • Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14688 TMEM18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TMEM18 MGD MGI:2387176
Felis catus TMEM18 VGNC VGNC:66295
Rattus norvegicus TMEM18 RGD RGD:1359389
Bos taurus TMEM18 VGNC VGNC:36006
Macaca mulatta TMEM18 VGNC VGNC:106238
Others TMEM18 NCBI