TMPRSS11B - transmembrane serine protease 11B Gene

Also Known as HATL5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 132724

About TMPRSS11B

This gene has 3 transcripts (splice variants), 487 orthologues and 17 paralogues. Restricted expression toward esophagus (RPKM 184.2).

Summary

Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMPRSS11B Products (1)

mRNA Protein Name
NM_182502.3 NP_872308.2 transmembrane protease serine 11B

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
24498351 GOA
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
24498351 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMPRSS11B Protein Structure

SEA

SEA: SEA domain (43 - 137)

Trypsin

Trypsin: Trypsin (185 - 410)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

transmembrane protease serine 11B

  • airway trypsin-like protease 5

Recombinant TMPRSS11B Proteins

Cat. No. Product Name Accession Purity
HY-P70869 TMPRSS11B Protein, Human (HEK293, His) Q86T26 (L39-L416) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14764 TMPRSS11B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20233 Tmprss11b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26740 Tmprss11b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMPRSS11B VGNC VGNC:107205
Mus musculus TMPRSS11B MGD MGI:2442893
Rattus norvegicus TMPRSS11B RGD RGD:1303278
Others TMPRSS11B NCBI