Etv2 - ets variant 2 Gene

Also Known as Etsrp71

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14008

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of endothelial cell differentiation; and positive regulation of mesoderm development. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system and hemolymphoid system. Orthologous to human ETV2 (ETS variant transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Etv2 Products (1)

mRNA Protein Name
NM_007959.2 NP_031985.2 ETS translocation variant 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12087183 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
12087183 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12087183 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within BMP signaling pathway IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within Wnt signaling pathway IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within blastocyst development IMP
IMP: Inferred from mutant phenotype
16630543 MGI
acts upstream of or within blood vessel morphogenesis IMP
IMP: Inferred from mutant phenotype
18462699 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
18462699 MGI
acts upstream of or within hemopoiesis IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
18462699 MGI
acts upstream of or within mesoderm formation IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
18462699 MGI
acts upstream of or within positive regulation of endothelial cell differentiation IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
18462699 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18462699 MGI
acts upstream of or within positive regulation of mesoderm development IDA
IDA: Inferred from direct assay
18462699 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12087183 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
16630543 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12087183 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS translocation variant 2

  • ets variant gene 2

  • ets-related protein 71

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04565 ETV2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174715 Human ETV2 mRNA / Unkown
HY-RS21336 Etv2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27855 Etv2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Etv2 NCBI NCBI:2116