P2ry14 - purinergic receptor P2Y, G-protein coupled, 14 Gene

Also Known as P2Y14; Gpr105; A330108O13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140795

About P2ry14

Chromosome 3: 59,021,276-59,061,039 reverse strand.GRCm39:CM000996.3

This gene has 9 transcripts (splice variants), 195 orthologues, 6 paralogues and is associated with 23 phenotypes. Broad expression in subcutaneous fat pad adult (RPKM 13.2), large intestine adult (RPKM 3.9) and 2 other tissues.

Summary

Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human P2RY14 (purinergic receptor P2Y14). [provided by Alliance of Genome Resources, Apr 2022]

P2ry14 Products (8)

mRNA Protein Name
NM_001287123.1 NP_001274052.1 P2Y purinoceptor 14 isoform a
NM_133200.4 NP_573463.1 P2Y purinoceptor 14 isoform a
NM_001287119.1 NP_001274048.1 P2Y purinoceptor 14 isoform a
NM_001287120.1 NP_001274049.1 P2Y purinoceptor 14 isoform a
NM_001287124.1 NP_001274053.1 P2Y purinoceptor 14 isoform b
NM_001287121.1 NP_001274050.1 P2Y purinoceptor 14 isoform a
NM_001008497.2 NP_001008497.1 P2Y purinoceptor 14 isoform a
NM_001287122.1 NP_001274051.1 P2Y purinoceptor 14 isoform a

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within hematopoietic stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
26880577 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry14 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (31 - 314)

7tm_GPCRs

7tm_GPCRs: cd14964 (33 - 57)

7tm_GPCRs

7tm_GPCRs: cd14964 (65 - 86)

7tm_GPCRs

7tm_GPCRs: cd14964 (103 - 125)

7tm_GPCRs

7tm_GPCRs: cd14964 (148 - 164)

7tm_GPCRs

7tm_GPCRs: cd14964 (192 - 215)

7tm_GPCRs

7tm_GPCRs: cd14964 (240 - 262)

7tm_GPCRs

7tm_GPCRs: cd14964 (282 - 307)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 14

  • G-protein coupled receptor 105

  • UDP-glucose receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09925 P2RY14 Human Pre-designed siRNA Set A / Unkown
HY-RS09926 P2ry14 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09927 P2ry14 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry14 NCBI NCBI:9934