Fbp1 - fructose bisphosphatase 1 Gene

Also Known as Fbp2; Fbp3; Fbp-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14121

Summary

Predicted to enable several functions, including cation binding activity; fructose 1,6-bisphosphate 1-phosphatase activity; and identical protein binding activity. Predicted to be involved in several processes, including cellular response to magnesium ion; hexose metabolic process; and regulation of cellular carbohydrate metabolic process. Predicted to be located in nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; facial bone primordium; ganglia; genitourinary system; and liver. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Fbp1 Products (1)

mRNA Protein Name
NM_019395.3 NP_062268.1 fructose-1,6-bisphosphatase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fructose 1,6-bisphosphate 1-phosphatase activity IMP
IMP: Inferred from mutant phenotype
30150719 MGI
Biological Process GO Annotation Evidence References Source
involved in gluconeogenesis IMP
IMP: Inferred from mutant phenotype
30150719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fructose-1,6-bisphosphatase 1

  • D-fructose-1,6-bisphosphate 1-phosphohydrolase 1

  • D-fructose-1,6-bisphosphate 1-phosphohydrolase 3

  • FBPase liver

  • fructose-1,6-bisphosphatase isozyme 3

  • liver FBPase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16309 MB-07803 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16307 MB05032 Inhibitor 99.63% Unkown
HY-RS17537 Fbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04779 FBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16758 Folr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17637 Fbp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23197 Folr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23994 Fbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbp1 NCBI NCBI:2203