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MB-07803 

Cat. No.: HY-16309
Handling Instructions

MB07803 is an orally available prodrug of a potent, noncompetitive inhibitor (MB07729) of fructose 1,6-bisphosphatase (FBPase), with EC50 of 140 nM and t1/2 of 7.6±2.9 h.

For research use only. We do not sell to patients.

MB-07803 Chemical Structure

MB-07803 Chemical Structure

CAS No. : 882757-24-6

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

MB07803 is an orally available prodrug of a potent, noncompetitive inhibitor (MB07729) of fructose 1,6-bisphosphatase (FBPase), with EC50 of 140 nM and t1/2 of 7.6±2.9 h.

IC50 & Target

31, 121, 189 nM for human, monkey, and rat, respectively [1] .

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7966 mL 8.9830 mL 17.9659 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL
10 mM 0.1797 mL 0.8983 mL 1.7966 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

556.61

Formula

C₂₄H₃₇N₄O₇PS

CAS No.

882757-24-6

SMILES

NC1=NC(C2=CC=C(P(NC(C)(C(OCC)=O)C)(NC(C)(C(OCC)=O)C)=O)O2)=C(C(C(C)(C)C)=O)S1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
MB-07803
Cat. No.:
HY-16309
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MB-07803

Cat. No.: HY-16309