MB-07803
MB-07803 is an orally active fructose-1,6-bisphosphatase (FBP1) inhibitor and a derivative of CS-917 (HY-14955). MB-07803 inhibits the rate-limiting enzyme in gluconeogenesis. MB07803 is converted as a prodrug to the active metabolite MB07729. MB-07803 controls blood glucose and is used in research on type 2 diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 882757-24-6
- 分子式: C24H37N4O7PS
- 分子量:556.61
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
31, 121, 189 nM for human, monkey, and rat, respectively [1] .
体外実験
MB-07803 is a prodrug form of an FBP1 inhibitor and a CS‑917 derivative that can be converted to generate the active metabolite MB07729[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
化学情報
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CAS 番号 882757-24-6
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分子量 556.61
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分子式 C24H37N4O7PS
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SMILES
O=C(C(C)(C)NP(NC(C)(C)C(OCC)=O)(C1=CC=C(C2=C(C(C(C)(C)C)=O)SC(N)=N2)O1)=O)OCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MB-07803 関連分類
HY-16309 関連分類
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