Fgf9 - fibroblast growth factor 9 Gene

Also Known as Eks; Fgf4b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14180

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity and growth factor activity. Involved in eye development. Acts upstream of or within several processes, including animal organ development; positive regulation of cell population proliferation; and positive regulation of signal transduction. Predicted to be located in basement membrane. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and sensory organ. Used to study lung cancer; multiple synostoses syndrome; and pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in multiple synostoses syndrome. Orthologous to human FGF9 (Fibroblast Growth Factor 9). [provided by Alliance of Genome Resources, Apr 2022]

Fgf9 Products (1)

mRNA Protein Name
NM_013518.4 NP_038546.2 fibroblast growth factor 9

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of Sertoli cell proliferation IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
16700629 MGI
acts upstream of activin receptor signaling pathway IDA
IDA: Inferred from direct assay
23034635 MGI
acts upstream of or within angiogenesis IDA
IDA: Inferred from direct assay
16778080 MGI
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
16778080 MGI
acts upstream of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
18533146 MGI
acts upstream of cardiac muscle cell proliferation IGI
IGI: Inferred from genetic interaction
15621532 MGI
acts upstream of cardiac muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
15621532 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of or within cell-cell signaling IMP
IMP: Inferred from mutant phenotype
15328018 MGI
acts upstream of or within chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
17544391 MGI
acts upstream of or within chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
17544391 MGI
acts upstream of or within embryonic digestive tract development IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
17576930 MGI
acts upstream of or within embryonic skeletal system development IMP
IMP: Inferred from mutant phenotype
17544391 MGI
acts upstream of epithelial cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
16308329 MGI
involved in eye development IMP
IMP: Inferred from mutant phenotype
21858205 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
15621532 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
15328018 MGI
acts upstream of or within lung development IDA
IDA: Inferred from direct assay
16540513 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
11493531 MGI
acts upstream of or within lung-associated mesenchyme development IMP
IMP: Inferred from mutant phenotype
18533146 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of or within male sex determination IGI
IGI: Inferred from genetic interaction
16700629 MGI
acts upstream of or within male sex determination IMP
IMP: Inferred from mutant phenotype
16700629 MGI
acts upstream of mesenchymal cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of mesenchymal cell proliferation IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of or within negative regulation of Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
16700629 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
17544391 MGI
acts upstream of or within positive regulation of activin receptor signaling pathway IDA
IDA: Inferred from direct assay
23034635 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
18533146 MGI
acts upstream of or within positive regulation of cardiac muscle cell proliferation IGI
IGI: Inferred from genetic interaction
15621532 MGI
acts upstream of or within positive regulation of cardiac muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
15621532 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
16185683 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
9847236 MGI
acts upstream of or within positive regulation of mesenchymal cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of or within positive regulation of mesenchymal cell proliferation IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of or within positive regulation of smoothened signaling pathway IDA
IDA: Inferred from direct assay
16540513 MGI
acts upstream of or within positive regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
16778080 MGI
acts upstream of or within positive regulation of stem cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of or within positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17544391 MGI
acts upstream of or within protein import into nucleus IMP
IMP: Inferred from mutant phenotype
15229180 MGI
acts upstream of or within regulation of timing of cell differentiation IMP
IMP: Inferred from mutant phenotype
17544391 MGI
acts upstream of smoothened signaling pathway IDA
IDA: Inferred from direct assay
16540513 MGI
acts upstream of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
16778080 MGI
acts upstream of stem cell proliferation IDA
IDA: Inferred from direct assay
16308329 MGI
acts upstream of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
16308329 MGI
acts upstream of vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17544391 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 9

  • FGF-9

  • GAF

  • HBGF-9

  • elbow knee synostosis

  • fibroblast growth factor 4b

  • glia-activating factor

Recombinant Fgf9 Proteins

Cat. No. Product Name Accession Purity
HY-P7352 FGF-9 Protein, Mouse (His, solution) P54130 (M1-S208) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P7352A FGF-9 Protein, Mouse (His) P54130 (A2-S208) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04907 FGF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174691 Human FGF9 mRNA / Unkown
HY-RS16698 Fgf9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23132 Fgf9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf9 NCBI NCBI:2254