Fosl1 - fos-like antigen 1 Gene

Also Known as Fra1; fra-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14283

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including in utero embryonic development; placenta blood vessel development; and vitellogenesis. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and presynaptic membrane. Predicted to be active in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; limb mesenchyme; and lung. Orthologous to human FOSL1 (FOS like 1, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Fosl1 Products (1)

mRNA Protein Name
NM_010235.2 NP_034365.1 fos-related antigen 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
19289495 MGI
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
30990796 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to stimulus IDA
IDA: Inferred from direct assay
9294610 MGI
acts upstream of or within cytokine-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
30990796 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
30990796 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
11044407 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
30990796 MGI
acts upstream of or within placenta blood vessel development IMP
IMP: Inferred from mutant phenotype
11044407 MGI
acts upstream of or within response to wounding IMP
IMP: Inferred from mutant phenotype
30990796 MGI
acts upstream of or within toll-like receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
30990796 MGI
acts upstream of or within vitellogenesis IMP
IMP: Inferred from mutant phenotype
11044407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fos-related antigen 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162723 FOSL1 degrader 1 Degrader 99.66% Unkown
HY-202699 SHOC2-RAS PPI-IN-1 Inhibitor 99.50% Unkown
HY-W019901B Anhydrous calcium sulfate (97%) Activator 99.40% Unkown
HY-RS05034 FOSL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18064 Fosl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24539 Fosl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fosl1 NCBI NCBI:8061