Fstl1 - follistatin-like 1 Gene

Also Known as Fstl; TSC-36

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14314

Summary

Predicted to enable calcium ion binding activity and heparin binding activity. Involved in endothelial cell differentiation; endothelial cell migration; and negative regulation of apoptotic process. Acts upstream of or within hematopoietic stem cell homeostasis. Located in extracellular space. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; limb; and sensory organ. Orthologous to human FSTL1 (Follistatin like 1). [provided by Alliance of Genome Resources, Apr 2022]

Fstl1 Products (1)

mRNA Protein Name
NM_008047.5 NP_032073.2 follistatin-related protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20054002 MGI
Biological Process GO Annotation Evidence References Source
involved in endothelial cell differentiation IMP
IMP: Inferred from mutant phenotype
20054002 MGI
involved in endothelial cell migration IDA
IDA: Inferred from direct assay
20054002 MGI
involved in endothelial cell migration IMP
IMP: Inferred from mutant phenotype
20054002 MGI
acts upstream of or within hematopoietic stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
26880577 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
20054002 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

follistatin-related protein 1

  • TGF-beta-inducible protein TSC-36

  • follistatin-like protein 1

Fstl1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Fstl1 Q62356 DIP2A Homo sapiens Q14689
Pull Down
20054002
Cross
Fstl1 Q62356 DIP2A Homo sapiens Q14689
Anti Tag CoIP
20054002
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Fstl1 Proteins

Cat. No. Product Name Accession Purity
HY-P70859 Follistatin-like 1/FSTL1 Protein, Mouse (HEK293, His) Q62356 (E19-I306) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05128 FSTL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16900 Fstl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23342 Fstl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fstl1 NCBI NCBI:11167