PRIMA1 - proline rich membrane anchor 1 Gene

Also Known as PRIMA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 145270

About PRIMA1

Cytogenetic location: 14q32.12 Genomic coordinates (GRCh38): 14:93,718,298-93,788,994 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele and 179 orthologues. Broad expression in esophagus (RPKM 7.2), endometrium (RPKM 3.8) and 19 other tissues.

Summary

The product of this gene functions to organize acetylcholinesterase (AChE) into tetramers, and to anchor AChE at neural cell membranes. [provided by RefSeq, Nov 2008]

PRIMA1 Products (1)

mRNA Protein Name
NM_178013.4 NP_821092.1 proline-rich membrane anchor 1 precursor
Protein Preferred Names Protein Names

proline-rich membrane anchor 1

  • acetylcholinesterase membrane anchor precursor PRiMA

Related Diseases

Diseases Alias
Li-Fraumeni Syndrome

  • Sarcoma Family Syndrome Of Li And Fraumeni

  • Sbla Syndrome

  • LFS

  • Li-Fraumeni Familiar Cancer Susceptibility Syndrome

  • Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

  • Lfs1

  • Li Fraumeni Syndrome

  • Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

  • Lfl

  • Sbla Syndrome Li-Fraumeni-Like Syndrome

  • Li-Fraumeni Syndrome 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-19980 Eprenetapopt 99.52% Phase 3
HY-19980G Eprenetapopt (GMP) / Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19980A PRIMA-1 98.0% Unkown
HY-122578 P53R3 p53 Inhibitor 99.93% Unkown
HY-RS11098 PRIMA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17477 Prima1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23935 Prima1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PRIMA1 RGD RGD:1583978
Mus musculus PRIMA1 MGD MGI:1926097
Bos taurus PRIMA1 VGNC VGNC:53948
Canis familiaris PRIMA1 VGNC VGNC:51672
Others PRIMA1 NCBI