Gpr12 - G-protein coupled receptor 12 Gene

Also Known as Gpcr01; Gpcr12; Gpcr20; Gpcr21

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14738

Summary

Enables phosphatidylcholine binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway and cellular calcium ion homeostasis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in central nervous system; gut; and liver. Used to study obesity. Orthologous to human GPR12 (G protein-coupled receptor 12). [provided by Alliance of Genome Resources, Apr 2022]

Gpr12 Products (6)

mRNA Protein Name
NM_001010941.2 NP_001010941.1 G-protein coupled receptor 12 isoform a
NM_001359055.1 NP_001345984.1 G-protein coupled receptor 12 isoform a
NM_001359056.1 NP_001345985.1 G-protein coupled receptor 12 isoform a
NM_001359057.1 NP_001345986.1 G-protein coupled receptor 12 isoform a
NM_001359058.1 NP_001345987.1 G-protein coupled receptor 12 isoform b precursor
NM_008151.3 NP_032177.1 G-protein coupled receptor 12 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phosphatidylcholine binding IDA
IDA: Inferred from direct assay
12574419 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12574419 MGI
acts upstream of or within intracellular calcium ion homeostasis IDA
IDA: Inferred from direct assay
12574419 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G-protein coupled receptor 12

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108496 Sphingosine-1-phosphate Agonist 99.94% Phase 1

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108496S Sphingosine-1-phosphate-d7 Agonist 99.9% Unkown
HY-183657A GPR3 inverse agonist-1 TFA / Unkown
HY-RS05655 GPR12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-167754 Resolvin D5 n-3 DPA Agonist / Unkown
HY-RS20031 Gpr12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26534 Gpr12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr12 NCBI NCBI:2835