Hadh - hydroxyacyl-Coenzyme A dehydrogenase Gene

Also Known as HCDH; Schad; Hadhsc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15107

Summary

Enables 3-hydroxyacyl-CoA dehydrogenase activity. Involved in positive regulation of cold-induced thermogenesis and regulation of Insulin secretion. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Hadh Products (1)

mRNA Protein Name
NM_008212.4 NP_032238.2 hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 3-hydroxyacyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
15240869 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20670938 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
21990309 MGI
involved in regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
20670938 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
26767982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

  • L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain

  • hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase

  • medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase

  • short-chain 3-hydroxyacyl-CoA dehydrogenase

Recombinant Hadh Proteins

Cat. No. Product Name Accession Purity
HY-P71563 HCDH Protein, Mouse (His-SUMO) Q61425-1 (S13-K314) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-178918 XZA-1 99.59% Unkown
HY-E70239 2-Methylbutyryl-CoA / Unkown
HY-RS05989 HADH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05990 HADHA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17745 Hadh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24211 Hadh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hadh NCBI NCBI:3033