Hdc - histidine decarboxylase Gene

Also Known as Hdc-a; Hdc-c; Hdc-e; Hdc-s

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15186

Summary

Enables histidine decarboxylase activity. Acts upstream of or within histamine biosynthetic process and histidine catabolic process. Predicted to be located in cytosol; dendrite; and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Hdc Products (1)

mRNA Protein Name
NM_008230.6 NP_032256.3 histidine decarboxylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histidine decarboxylase activity IMP
IMP: Inferred from mutant phenotype
11478947 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within L-histidine catabolic process IMP
IMP: Inferred from mutant phenotype
11478947 MGI
acts upstream of or within histamine biosynthetic process IMP
IMP: Inferred from mutant phenotype
11478947 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histidine decarboxylase

  • L-histidine decarboxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W003445 4-Bromo-3-hydroxybenzoic acid 99.25% Unkown
HY-146159 PI3K/HDAC-IN-2 Inhibitor / Unkown
HY-186122 CCK2R agonist-1 Agonist / Unkown
HY-RS06091 HDC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06106 HECA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W194107 Antitumor agent-152 Inhibitor / Unkown
HY-RS17727 Hdc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24192 Hdc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdc NCBI NCBI:3067