CTSW - cathepsin W Gene

Also Known as LYPN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1521

About CTSW

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:65,879,837-65,883,741 (from NCBI)

This gene has 8 transcripts (splice variants), 454 orthologues and 12 paralogues. Biased expression in bone marrow (RPKM 42.0), spleen (RPKM 24.6) and 12 other tissues.

Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]

CTSW Products (1)

mRNA Protein Name
NM_001335.4 NP_001326.3 cathepsin W preproprotein

CTSW Protein Structure

Inhibitor_I29

Inhibitor_I29: Cathepsin propeptide inhibitor domain (I29) (42 - 99)

Peptidase_C1

Peptidase_C1: Papain family cysteine protease (128 - 359)

  • 0
  • 100
  • 200
  • 300
  • 376 a.a.
Protein Preferred Names Protein Names

cathepsin W

  • lymphopain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS03348 CTSW Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18753 Ctsw Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25240 Ctsw Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CTSW VGNC VGNC:61272
Mus musculus CTSW MGD MGI:1338045
Canis familiaris CTSW VGNC VGNC:39716
Bos taurus CTSW VGNC VGNC:27819
Macaca mulatta CTSW VGNC VGNC:71563
Rattus norvegicus CTSW RGD RGD:1309354
Others CTSW NCBI