1. Gene
  2. Hrh2 - histamine receptor H2 Gene

Hrh2 - histamine receptor H2 Gene

Mus musculus

Also known as H2R; HH2R

Gene ID: 15466 | Gene type: protein coding

About Hrh2

Chromosome 13: 54,346,148-54,390,199 forward strand.GRCm39:CM001006.3

This gene has 3 transcripts (splice variants), 249 orthologues, 32 paralogues and is associated with 15 phenotypes. Broad expression in frontal lobe adult (RPKM 1.9), stomach adult (RPKM 1.8) and 18 other tissues.

Summary

Predicted to enable G protein-coupled amine receptor activity; heterocyclic compound binding activity; and neurotransmitter receptor activity. Acts upstream of or within several processes, including gastric acid secretion; learning or memory; and toxin transport. Predicted to be located in membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in brain; early conceptus; stomach; and uterus. Orthologous to human HRH2 (Histamine Receptor H2). [provided by Alliance of Genome Resources, Apr 2022]

Hrh2 Products(2)

mRNA Protein Name
NM_001413010.1 NP_001399939.1 histamine H2 receptor isoform 3
NM_001010973.3 NP_001010973.1 histamine H2 receptor isoform 1

Hrh2 Protein Structure

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (18 - 297)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (19 - 45)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (52 - 79)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (90 - 120)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (132 - 152)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (177 - 207)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (225 - 255)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (265 - 290)

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  • 397 a.a.
Protein Preferred Names Protein Names

histamine H2 receptor

gastric receptor I

Orthologs Information

Species Symbol Source ID
Homo sapiens Hrh2 NCBI NCBI:3274