Htr6 - 5-hydroxytryptamine (serotonin) receptor 6 Gene

Mus musculus

Also known as 5-HT6

Gene ID: 15565 | Gene type: protein coding

About Htr6

Chromosome 4: 138,788,419-138,802,881 reverse strand.GRCm39:CM000997.3

This gene has 2 transcripts (splice variants), 114 orthologues, 9 paralogues and is associated with 7 phenotypes. Biased expression in cortex adult (RPKM 1.8), frontal lobe adult (RPKM 1.5) and 11 other tissues.

Summary

Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Involved in cerebral cortex cell migration and positive regulation of TOR signaling. Located in cilium. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; and cortical plate. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human HTR6 (5-hydroxytryptamine receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Htr6 Products(2)

mRNA	Protein	Name
NM_001377096.1	NP_001364025.1	5-hydroxytryptamine receptor 6
NM_021358.2	NP_067333.1	5-hydroxytryptamine receptor 6

Htr6 Protein Structure

7tmA_5-HT6

0
100
200
300
400
440 a.a.

Protein Preferred Names

Protein Names

5-hydroxytryptamine receptor 6

5-HT-6

serotonin receptor 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS06480	HTR6 Human Pre-designed siRNA Set A	/	Unkown
HY-RS06481	Htr6 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS06482	Htr6 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Htr6	NCBI	NCBI:3362

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