Igfbp4 - insulin-like growth factor binding protein 4 Gene

Also Known as Deb2; IBP-4; IGFBP-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16010

Summary

Enables insulin-like growth factor binding activity. Acts upstream of or within several processes, including positive regulation of signal transduction; regulation of glucose metabolic process; and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; early embryo; female reproductive system; limb; and lung. Orthologous to human IGFBP4 (Insulin like growth factor binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp4 Products (1)

mRNA Protein Name
NM_010517.4 NP_034647.1 insulin-like growth factor-binding protein 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables insulin-like growth factor binding IPI
IPI: Inferred from physical interaction
7679139 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18528331 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of MAPK cascade IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within positive regulation of insulin-like growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within regulation of cell growth IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within regulation of glucose metabolic process IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within regulation of growth IGI
IGI: Inferred from genetic interaction
16675541 MGI
acts upstream of or within type B pancreatic cell proliferation IGI
IGI: Inferred from genetic interaction
16675541 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
7510770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 4

  • Band 3A

  • IGF-binding protein 4

  • differentially expressed in B16F10 2

Recombinant Igfbp4 Proteins

Cat. No. Product Name Accession Purity
HY-P74845 IGFBP-4 Protein, Mouse (HEK293, His) P47879 (D22-E254) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06627 IGFBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174649 Human IGFBP4 mRNA / Unkown
HY-RS19779 Igfbp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26276 Igfbp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igfbp4 NCBI NCBI:3487