Il15ra - interleukin 15 receptor, alpha chain Gene
Also Known as IL-15RA
Species: Mus musculus
Summary
Predicted to enable interleukin-15 receptor activity and protein kinase binding activity. Acts upstream of or within positive regulation of natural killer cell differentiation. Located in cytoplasmic vesicle and plasma membrane. Is expressed in central nervous system; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human IL15RA (interleukin 15 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]
Il15ra Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271497.1 | NP_001258426.1 | interleukin-15 receptor subunit alpha isoform 2 |
| NM_001271498.1 | NP_001258427.1 | interleukin-15 receptor subunit alpha isoform 3 |
| NM_001271499.1 | NP_001258428.1 | interleukin-15 receptor subunit alpha isoform 4 precursor |
| NM_001271500.1 | NP_001258429.1 | interleukin-15 receptor subunit alpha isoform 5 precursor |
| NM_001271501.1 | NP_001258430.1 | interleukin-15 receptor subunit alpha isoform 6 precursor |
| NM_008358.2 | NP_032384.1 | interleukin-15 receptor subunit alpha isoform 1 precursor |
| NM_133836.2 | NP_598597.1 | interleukin-15 receptor subunit alpha isoform 2 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of natural killer cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
14607906 | MGI |
| acts upstream of or within positive regulation of natural killer cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
14607906 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasmic vesicle |
IDA
IDA: Inferred from direct assay
|
20374432 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
interleukin-15 receptor subunit alpha |
|
Recombinant Il15ra Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71978 | IL-15R alpha Protein, Mouse (HEK293, hFc) | Q60819-1 (G33-K205) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P78558 | IL-15R alpha & IL-15 Protein, Mouse (HEK293, His) | Q60819-1 (G33-K205) & P48346 (G30-S162) | ≥ 95%, as determined by reducing SDS-PAGE. |