Itgb7 - integrin beta 7 Gene

Also Known as Ly69

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16421

Summary

Predicted to enable Integrin binding activity. Acts upstream of or within T cell migration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of Integrin alpha4-beta7 complex. Predicted to be active in cell surface and focal adhesion. Is expressed in genitourinary system and thymus primordium. Orthologous to human ITGB7 (Integrin subunit beta 7). [provided by Alliance of Genome Resources, Apr 2022]

Itgb7 Products (1)

mRNA Protein Name
NM_013566.2 NP_038594.2 integrin beta-7 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell migration IMP
IMP: Inferred from mutant phenotype
23661644 MGI
acts upstream of or within leukocyte migration IMP
IMP: Inferred from mutant phenotype
15484189 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin beta-7

  • M290 IEL antigen

  • integrin beta-P

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99184 Abrilumab 98.35% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06971 ITGB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-185661 IBS007125 Inhibitor / Unkown
HY-RS18178 Itgb7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24652 Itgb7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb7 NCBI NCBI:3695