Jund - jun D proto-oncogene Gene

Also Known as Jund1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16478

Summary

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and Apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]

Jund Products (2)

mRNA Protein Name
NM_001286944.1 NP_001273873.1 transcription factor JunD isoform deltaJunD
NM_010592.5 NP_034722.1 transcription factor JunD isoform JunD-FL

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12220541 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
2504580 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
2504580 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10837920 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
2504580 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22974638 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
22990073 MGI
enables transcription coregulator binding IPI
IPI: Inferred from physical interaction
10523647 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to calcium ion IDA
IDA: Inferred from direct assay
19303854 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
22990073 MGI
acts upstream of or within osteoblast development IGI
IGI: Inferred from genetic interaction
15563473 MGI
acts upstream of or within positive regulation of osteoblast differentiation IGI
IGI: Inferred from genetic interaction
15563473 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
2504580 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19303854 MGI
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
10523647 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor JunD

  • Jun proto-oncogene related gene d

  • Jun proto-oncogene related gene d1

  • transcription factor AP-1 subunit JunD

  • transcription factor jun-D

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07060 JUND Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19345 Jund Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179594 HTS10307 Inhibitor / Unkown
HY-182050 YL0441 Inhibitor / Unkown
HY-W471288 JPC0661 Inhibitor / Unkown
HY-N11231 Fucoxanthinol / Unkown
HY-RS25836 Jund Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jund NCBI NCBI:3727