HTS10307
HTS10307 is a small molecule AP1 Transcription Factor ΔFOSB inhibitor. HTS10307 inhibits the binding of ΔFOSB/JUND and ΔFOSB to DNA with IC50 values of ~3 μM and ~7 μM, respectively. HTS10307 can be used as a chemical probe for investigating the role of ΔFOSB in pathological conditions such as drug addiction, Alzheimer’s disease, and Parkinson’s disease.
For research use only. We do not sell to patients.
- CAS No.: 81682-91-9
- Formula: C14H8N2O2S
- Molecular Weight:268.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All AP-1 Isoforms
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Biological Activity
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FosB |
Chemical Information
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CAS No. 81682-91-9
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Molecular Weight 268.29
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Formula C14H8N2O2S
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SMILES
O=C(N1)C(C#N)=C(C2=CC=CO2)C=C1C3=CC=CS3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)