HTS10307
Based on 1 Customer Validation
HTS10307 is a small molecule AP1 Transcription Factor ΔFOSB inhibitor. HTS10307 inhibits the binding of ΔFOSB/JUND and ΔFOSB to DNA with IC50 values of ~3 μM and ~7 μM, respectively. HTS10307 can be used as a chemical probe for investigating the role of ΔFOSB in pathological conditions such as drug addiction, Alzheimer’s disease, and Parkinson’s disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.29%
- CAS 番号: 81682-91-9
- 分子式: C14H8N2O2S
- 分子量:268.29
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
AP-1 アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
FosB |
化学情報
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CAS 番号 81682-91-9
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性状 Solid
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分子量 268.29
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分子式 C14H8N2O2S
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Color Light brown to yellow
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SMILES
O=C(N1)C(C#N)=C(C2=CC=CO2)C=C1C3=CC=CS3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (372.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7273 mL | 18.6365 mL | 37.2731 mL | 93.1827 mL |
| 5 mM | 0.7455 mL | 3.7273 mL | 7.4546 mL | 18.6365 mL | |
| 10 mM | 0.3727 mL | 1.8637 mL | 3.7273 mL | 9.3183 mL | |
| 15 mM | 0.2485 mL | 1.2424 mL | 2.4849 mL | 6.2122 mL | |
| 20 mM | 0.1864 mL | 0.9318 mL | 1.8637 mL | 4.6591 mL | |
| 25 mM | 0.1491 mL | 0.7455 mL | 1.4909 mL | 3.7273 mL | |
| 30 mM | 0.1242 mL | 0.6212 mL | 1.2424 mL | 3.1061 mL | |
| 40 mM | 0.0932 mL | 0.4659 mL | 0.9318 mL | 2.3296 mL | |
| 50 mM | 0.0745 mL | 0.3727 mL | 0.7455 mL | 1.8637 mL | |
| 60 mM | 0.0621 mL | 0.3106 mL | 0.6212 mL | 1.5530 mL | |
| 80 mM | 0.0466 mL | 0.2330 mL | 0.4659 mL | 1.1648 mL | |
| 100 mM | 0.0373 mL | 0.1864 mL | 0.3727 mL | 0.9318 mL |
HTS10307 関連分類
HY-179594 関連分類
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