Kera - keratocan Gene

Also Known as KTN; CNA2; SLRR2B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16545

Summary

Acts upstream of or within cornea development in camera-type eye. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; cranial muscle; jaw; limb mesenchyme; and sensory organ. Used to study cornea plana. Human ortholog(s) of this gene implicated in arcus senilis; cornea plana; and corneal dystrophy. Orthologous to human KERA (keratocan). [provided by Alliance of Genome Resources, Apr 2022]

Kera Products (1)

mRNA Protein Name
NM_008438.3 NP_032464.1 keratocan precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cornea development in camera-type eye IMP
IMP: Inferred from mutant phenotype
10802664 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

keratocan

  • keratan sulfate proteoglycan keratocan

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-E70193 Keratinase Degrader / Phase 4

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07234 KERA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18482 Kera Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24963 Kera Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kera NCBI NCBI:11081