Uhmk1 - U2AF homology motif (UHM) kinase 1 Gene

Also Known as KIS; Kist; P-CIP2; 4732477C12Rik; 4930500M09Rik; C820018A03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16589

Summary

Enables ribonucleoprotein complex binding activity. Involved in neuron projection development and positive regulation of translational initiation. Located in axon; dendrite cytoplasm; and neuronal ribonucleoprotein granule. Is expressed in brain; heart; liver; metanephros; and musculature. Orthologous to human UHMK1 (U2AF homology motif kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Uhmk1 Products (2)

mRNA Protein Name
NM_001360809.1 NP_001347738.1 serine/threonine-protein kinase Kist isoform 2
NM_010633.4 NP_034763.3 serine/threonine-protein kinase Kist isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
7724523 MGI
enables ribonucleoprotein complex binding IDA
IDA: Inferred from direct assay
19015237 MGI
Biological Process GO Annotation Evidence References Source
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
19015237 MGI
involved in positive regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
19015237 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
19015237 MGI
located in dendrite cytoplasm IDA
IDA: Inferred from direct assay
19015237 MGI
located in neuronal ribonucleoprotein granule IDA
IDA: Inferred from direct assay
19015237 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase Kist

  • PAM COOH-terminal interactor protein 2

  • U2AF homology motif kinase 1

  • kinase interacting with leukemia-associated gene (stathmin)

  • kinase interacting with stathmin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-RS15444 UHMK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22895 Uhmk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uhmk1 NCBI NCBI:127933