Blnk - B cell linker Gene

Also Known as Bca; BASH; Ly57; Ly-57; Lyw-57; SLP-65

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17060

Summary

Predicted to enable SH2 domain binding activity; enzyme binding activity; and signaling adaptor activity. Involved in positive regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including genitourinary system; gut; immune system; lung; and olfactory epithelium. Human ortholog(s) of this gene implicated in agammaglobulinemia and agammaglobulinemia 4. Orthologous to human BLNK (B cell linker). [provided by Alliance of Genome Resources, Apr 2022]

Blnk Products (2)

mRNA Protein Name
NM_001365054.1 NP_001351983.1 B-cell linker protein isoform 2
NM_008528.5 NP_032554.2 B-cell linker protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15196959 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22949502 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15196959 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

B-cell linker protein

  • B-cell adapter containing a SH2 domain protein

  • B-cell adapter containing a Src homology 2 domain protein

  • cytoplasmic adapter protein

  • lymphocyte antigen 57

  • src homology 2 domain-containing leukocyte protein of 65 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01522 BLNK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21300 Blnk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27819 Blnk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Blnk NCBI NCBI:29760