Capn8 - calpain 8 Gene

Also Known as nCL-2; nCL-2'

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170725

Summary

Enables calcium-dependent cysteine-type endopeptidase activity and identical protein binding activity. Acts upstream of or within calcium-dependent self proteolysis. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. Is expressed in gut; liver; and male reproductive gland or organ. Orthologous to human CAPN8 (calpain 8). [provided by Alliance of Genome Resources, Apr 2022]

Capn8 Products (2)

mRNA Protein Name
NM_001145806.1 NP_001139278.1 calpain-8 isoform 2
NM_130890.2 NP_570960.2 calpain-8 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent cysteine-type endopeptidase activity IDA
IDA: Inferred from direct assay
17646163 MGI
enables calcium-dependent cysteine-type endopeptidase activity IMP
IMP: Inferred from mutant phenotype
17646163 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
17646163 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium-dependent self proteolysis IDA
IDA: Inferred from direct assay
17646163 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calpain-8

  • new calpain 2

  • stomach-specific M-type calpain

  • stomach-specific calpain (nCL-2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01893 CAPN8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22412 Capn8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28936 Capn8 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Capn8 NCBI NCBI:388743