Mutyh - mutY DNA glycosylase Gene

Also Known as Myh

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170841

Summary

Enables DNA N-glycosylase activity. Involved in response to oxidative stress. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Mutyh Products (1)

mRNA Protein Name
NM_133316.2 NP_579850.2 adenine DNA glycosylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
14690527 RGD
Biological Process GO Annotation Evidence References Source
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
12472901 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenine DNA glycosylase

  • a/G-specific adenine DNA glycosylase

  • mutY homolog

  • rMYH

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08854 MUTYH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22658 Mutyh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29172 Mutyh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mutyh NCBI NCBI:4595