Stk17b - serine/threonine kinase 17b Gene

Also Known as Drak2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170904

Summary

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in apoptotic process; intracellular signal transduction; and protein autophosphorylation. Located in actin Cytoskeleton and nucleus. Orthologous to human STK17B (serine/threonine kinase 17b). [provided by Alliance of Genome Resources, Apr 2022]

Stk17b Products (1)

mRNA Protein Name
NM_133392.1 NP_596883.1 serine/threonine-protein kinase 17B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
11481038 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11481038 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
12966074 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
11481038 RGD
Biological Process GO Annotation Evidence References Source
involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
11481038 RGD
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
11481038 RGD
involved in programmed cell death IDA
IDA: Inferred from direct assay
11481038 RGD
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
12966074 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
11481038 RGD
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
11481038 RGD
located in nucleus IDA
IDA: Inferred from direct assay
11481038 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase 17B

  • DAP kinase-related apoptosis-inducing protein kinase 2

  • death-associated protein kinase-related 2

  • serine/threonine kinase 17b (apoptosis-inducing)

Stk17b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Stk17b Q91XS8 Rhov Rattus norvegicus Q9Z1Y0
Y2H
11481038
Intra
Stk17b Q91XS8 Chp1 Rattus norvegicus P61023
IF
21374135
Intra
Stk17b Q91XS8 Chp1 Rattus norvegicus P61023
Y2H
21374135
Intra
Stk17b Q91XS8 Chp1 Rattus norvegicus P61023
Pull Down
12966074
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156350 SGC-STK17B-1 Inhibitor 98.53% Unkown
HY-148062 RSS0680 Degrader 99.85% Unkown
HY-186224 GW296115 / Unkown
HY-RS13925 STK17B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stk17b NCBI NCBI:9262