Mtdh - metadherin Gene

Also Known as Lyric

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170910

Summary

Predicted to enable NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in bicellular tight junction assembly. Located in several cellular components, including apical plasma membrane; bicellular tight junction; and intercellular canaliculus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MTDH (metadherin). [provided by Alliance of Genome Resources, Apr 2022]

Mtdh Products (1)

mRNA Protein Name
NM_133398.2 NP_596889.1 protein LYRIC

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in bicellular tight junction assembly IEP
IEP: Inferred from expression pattern
15383321 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15383321 RGD
located in bicellular tight junction IDA
IDA: Inferred from direct assay
15383321 RGD
located in intercellular canaliculus IDA
IDA: Inferred from direct assay
15383321 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15383321 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein LYRIC

  • LYRIC

  • lysine-rich CEACAM1 co-isolated protein

  • metastasis adhesion protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155170 MTDH-SND1 blocker 1 Inhibitor 99.33% Unkown
HY-160801 HKYK-0030 Inhibitor 99.38% Unkown
HY-168850 MTDH-SND1 blocker 2 Inducer 99.51% Unkown
HY-RS08762 MTDH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18775 Mtdh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25263 Mtdh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtdh NCBI NCBI:92140