MTDH-SND1 blocker 2
Based on 1 Customer Validation
MTDH-SND1 blocker 2 (compound C19) is a potent MTDH-SND1 blocker with an IC50 value of 487 nM. MTDH-SND1 blocker 2 binds to the SND1 protein with a Kd value of 279 nM. MTDH-SND1 blocker 2 degrades SND1 protein. MTDH-SND1 blocker 2 shows antiproliferative activity and induces apoptosis. MTDH-SND1 blocker 2 has the potential for the research of breast cancer.
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- Reinheit: 99.51%
- CAS. Nr.: 3052204-80-2
- Formel: C18H12FN3O2S
- Molecular Weight:353.37
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
IC50: 487 nM (MTDH-SND1)[1]
Chemical Information
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CAS. Nr. 3052204-80-2
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Appearance Solid
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Molecular Weight 353.37
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Formel C18H12FN3O2S
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Color White to off-white
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SMILES
FC1=CC(C=CC=N2)=C2C(NS(C3=C(N=CC=C4)C4=CC=C3)(=O)=O)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8299 mL | 14.1495 mL | 28.2990 mL | 70.7474 mL |
| 5 mM | 0.5660 mL | 2.8299 mL | 5.6598 mL | 14.1495 mL | |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8299 mL | 7.0747 mL | |
| 15 mM | 0.1887 mL | 0.9433 mL | 1.8866 mL | 4.7165 mL | |
| 20 mM | 0.1415 mL | 0.7075 mL | 1.4149 mL | 3.5374 mL | |
| 25 mM | 0.1132 mL | 0.5660 mL | 1.1320 mL | 2.8299 mL | |
| 30 mM | 0.0943 mL | 0.4716 mL | 0.9433 mL | 2.3582 mL |