Mgat1 - mannoside acetylglucosaminyltransferase 1 Gene

Also Known as Mgat-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17308

Summary

Enables acetylglucosaminyltransferase activity. Acts upstream of or within UDP-N-acetylglucosamine catabolic process and in utero embryonic development. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including decidua; early conceptus; embryo ectoderm; embryo endoderm; and retina outer nuclear layer. Orthologous to human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mgat1 Products (4)

mRNA Protein Name
NM_001110148.1 NP_001103618.1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NM_001110149.1 NP_001103619.1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NM_001110150.1 NP_001103620.1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NM_010794.3 NP_034924.3 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
1421759 MGI
enables acetylglucosaminyltransferase activity IMP
IMP: Inferred from mutant phenotype
8290590 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within UDP-N-acetylglucosamine catabolic process IDA
IDA: Inferred from direct assay
1421759 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
8290590 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

  • GNT-I

  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I

  • glcNAc-T I

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-138942 PF-06427878 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103504 (S)-SNAP5114 Inhibitor 98.09% Unkown
HY-118207 LU-32-176B Inhibitor / Unkown
HY-155305 BuChE-IN-9 Inhibitor / Unkown
HY-185701 W-GTF01 Inhibitor / Unkown
HY-E70144 N-Acetylglucosaminyltransferase 1 / Unkown
HY-RS08399 MGAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08584 MOGAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21645 Mgat1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28163 Mgat1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgat1 NCBI NCBI:4245