Osmr - oncostatin M receptor Gene

Also Known as OSMRB

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18414

Summary

Enables cytokine binding activity and oncostatin-M receptor activity. Predicted to be involved in oncostatin-M-mediated signaling pathway and positive regulation of cell population proliferation. Predicted to act upstream of or within cell surface receptor signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system; hemolymphoid system; lung; sensory organ; and skeletal system. Human ortholog(s) of this gene implicated in primary localized cutaneous amyloidosis 1. Orthologous to human OSMR (oncostatin M receptor). [provided by Alliance of Genome Resources, Apr 2022]

Osmr Products (4)

mRNA Protein Name
NM_001310469.2 NP_001297398.1 oncostatin-M-specific receptor subunit beta isoform 2 precursor
NM_011019.4 NP_035149.2 oncostatin-M-specific receptor subunit beta isoform 1 precursor
NM_001310469.2 NP_001297398.1 oncostatin-M-specific receptor subunit beta isoform 2 precursor
NM_011019.4 NP_035149.2 oncostatin-M-specific receptor subunit beta isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine binding IPI
IPI: Inferred from physical interaction
21182835 MGI
enables oncostatin-M receptor activity IDA
IDA: Inferred from direct assay
9920829 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
21182835 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oncostatin-M-specific receptor subunit beta

  • IL-31 receptor subunit beta

  • IL-31R subunit beta

  • IL-31R-beta

  • IL-31RB

  • interleukin-31 receptor subunit beta

  • oncostatin receptor

Recombinant Osmr Proteins

Cat. No. Product Name Accession Purity
HY-P78333 OSMR beta Protein, Mouse (HEK293, His) O70458 (E24-M737) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09851 OSMR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17541 Osmr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23999 Osmr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osmr NCBI NCBI:9180