Phf2 - PHD finger protein 2 Gene

Also Known as GRC5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18676

Summary

Enables histone H4-methyl-lysine-20 demethylase activity. Involved in epigenetic maintenance of chromatin in transcription-competent conformation; histone H3-K9 demethylation; and histone H4-K20 demethylation. Predicted to be located in kinetochore; nucleolus; and nucleoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human PHF2 (PHD finger protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Phf2 Products (1)

mRNA Protein Name
NM_011078.3 NP_035208.2 lysine-specific demethylase PHF2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone H4K20 demethylase activity IMP
IMP: Inferred from mutant phenotype
22921934 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22921934 MGI
Biological Process GO Annotation Evidence References Source
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
22921934 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase PHF2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10413 PHF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10420 PHF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19628 Phf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phf2 NCBI NCBI:5253