Prss8 - serine protease 8 Gene

Also Known as CAP1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192107

Summary

Predicted to enable Sodium Channel regulator activity. Involved in several processes, including positive regulation of sodium ion transmembrane transport; response to mineralocorticoid; and response to peptide hormone. Located in extracellular space. Used to study alopecia. Orthologous to human PRSS8 (serine protease 8). [provided by Alliance of Genome Resources, Apr 2022]

Prss8 Products (1)

mRNA Protein Name
NM_138836.1 NP_620191.1 prostasin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of sodium ion transmembrane transport IDA
IDA: Inferred from direct assay
11373334 RGD
involved in response to mineralocorticoid IEP
IEP: Inferred from expression pattern
17468916 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
16528252 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12506133 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
12506133 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostasin

  • channel-activating protease 1

  • protease, serine, 8

Recombinant Prss8 Proteins

Cat. No. Product Name Accession Purity
HY-P77155 Prostasin/PRSS8 Protein, Rat (HEK293, His) Q9ES87 (A30-R322) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11259 PRSS8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18185 Prss8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24659 Prss8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prss8 NCBI NCBI:5652