Acot2 - acyl-CoA thioesterase 2 Gene

Also Known as Mte1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192272

Summary

Enables palmitoyl-CoA hydrolase activity. Involved in several processes, including response to epidermal growth factor; response to hypoxia; and very long-chain fatty acid catabolic process. Located in mitochondrion. Used to study type 2 diabetes mellitus. Orthologous to human ACOT2 (acyl-CoA thioesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

Acot2 Products (1)

mRNA Protein Name
NM_138907.3 NP_620262.2 acyl-coenzyme A thioesterase 2, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
9445388 RGD
enables long-chain fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
7744868 RGD
Biological Process GO Annotation Evidence References Source
involved in long-chain fatty-acyl-CoA catabolic process IDA
IDA: Inferred from direct assay
7744868 RGD
involved in response to epidermal growth factor IEP
IEP: Inferred from expression pattern
18388199 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
12692085 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
15292030 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
15292030 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17438340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-coenzyme A thioesterase 2, mitochondrial

  • ARTISt/p43

  • MTE-I

  • acyl coenzyme A thioester hydrolase

  • mitochondrial acyl-CoA thioesterase 1

  • very-long-chain acyl-CoA thioesterase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00177 ACOT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22372 Acot2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28895 Acot2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acot2 NCBI NCBI:10965