Reg3a - regenerating islet-derived 3 alpha Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19694

Summary

Predicted to enable several functions, including identical protein binding activity; oligosaccharide binding activity; and peptidoglycan binding activity. Involved in negative regulation of keratinocyte differentiation; positive regulation of keratinocyte proliferation; and positive regulation of wound healing. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut and pancreas. Orthologous to human REG3A (regenerating family member 3 alpha) and REG3G (regenerating family member 3 gamma). [provided by Alliance of Genome Resources, Apr 2022]

Reg3a Products (1)

mRNA Protein Name
NM_011259.1 NP_035389.1 regenerating islet-derived protein 3-alpha precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of keratinocyte differentiation IDA
IDA: Inferred from direct assay
22727489 MGI
involved in positive regulation of keratinocyte proliferation IDA
IDA: Inferred from direct assay
22727489 MGI
involved in positive regulation of wound healing IDA
IDA: Inferred from direct assay
22727489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regenerating islet-derived protein 3-alpha

  • REG-3-alpha

  • RegIII (alpha)

  • generating islet-derived, mouse homolog 3 alpha

  • islet of Langerhans regenerating protein 3

  • lithostathine 3

  • pancreatitis-associated protein 2

  • reg III-alpha

  • regenerating islet-derived protein III-alpha

Recombinant Reg3a Proteins

Cat. No. Product Name Accession Purity
HY-P76568 REG-3 alpha/REG3A Protein, Mouse (HEK293, His) NP_035389 (E27-Q175) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18839 Reg3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11820 REG3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25331 Reg3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Reg3a NCBI NCBI:5068