Ren1 - renin 1 structural Gene

Mus musculus

Also known as Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d

Gene ID: 19701 | Gene type: protein coding

About Ren1

Chromosome 1: 133,278,248-133,288,063 forward strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 220 orthologues, 8 paralogues and is associated with 57 phenotypes. Biased expression in kidney adult (RPKM 87.3) and ovary adult (RPKM 3.3).

Summary

Enables endopeptidase activity. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (Renin). [provided by Alliance of Genome Resources, Apr 2022]

Ren1 Products(1)

mRNA	Protein	Name
NM_031192.3	NP_112469.1	renin-1 precursor

Ren1 Protein Structure

A1_Propeptide

renin_like

0
100
200
300
402 a.a.

Protein Preferred Names

Protein Names

renin-1

angiotensinogenase	aspartyl-protease
kidney renin	renin b

Recombinant Ren1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71081	Renin Protein, Mouse (HEK293, His)	P06281 (L22-R402)	≥95%