Ren1 - renin 1 structural Gene

Also Known as Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19701

About Ren1

Chromosome 1: 133,278,248-133,288,063 forward strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 220 orthologues, 8 paralogues and is associated with 57 phenotypes. Biased expression in kidney adult (RPKM 87.3) and ovary adult (RPKM 3.3).

Summary

Enables endopeptidase activity. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (Renin). [provided by Alliance of Genome Resources, Apr 2022]

Ren1 Products (1)

mRNA Protein Name
NM_031192.3 NP_112469.1 renin-1 precursor

Ren1 Protein Structure

A1_Propeptide

A1_Propeptide: pfam07966 (30 - 48)

renin_like

renin_like: cd05487 (75 - 400)

  • 0
  • 100
  • 200
  • 300
  • 402 a.a.
Protein Preferred Names Protein Names

renin-1

  • angiotensinogenase

  • aspartyl-protease

  • kidney renin

  • renin b

Recombinant Ren1 Proteins

Cat. No. Product Name Accession Purity
HY-P71081 Renin Protein, Mouse (HEK293, His) P06281 (L22-R402) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11840 Ren Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11841 Ren1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown