PATL2 - PAT1 homolog 2 Gene

Homo sapiens

Also known as OOMD4; Pat1a; hPat1a

Gene ID: 197135 | Gene type: protein coding

About PATL2

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:44,665,732-44,711,390 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 179 orthologues, 1 paralogue and is associated with 2 phenotypes. Broad expression in spleen (RPKM 2.6), lymph node (RPKM 2.5) and 20 other tissues.

Summary

Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PATL2 Products(7)

mRNA	Protein	Name
NM_001145112.2	NP_001138584.1	protein PAT1 homolog 2 isoform 1
NM_001330283.2	NP_001317212.1	protein PAT1 homolog 2 isoform 2
NM_001387260.1	NP_001374189.1	protein PAT1 homolog 2 isoform 3
NM_001387261.1	NP_001374190.1	protein PAT1 homolog 2 isoform 1
NM_001387262.1	NP_001374191.1	protein PAT1 homolog 2 isoform 1
NM_001387263.1	NP_001374192.1	protein PAT1 homolog 2 isoform 1
NM_001387264.1	NP_001374193.1	protein PAT1 homolog 2 isoform 3

PATL2 Protein Structure

PAT1

0
100
200
300
400
500
543 a.a.

Protein Preferred Names

Protein Names

protein PAT1 homolog 2

PAT1-like protein 2

Related Diseases

Diseases

Alias

Oocyte Maturation Defect 4

OOMD4

Oocyte Maturation Defect, Type 4

Female Infertility Due To Oocyte Meiotic Arrest

Oocyte Maturation Defect 2

OOMD2

Oocyte Maturation Defect, Type 2

Infertility

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10085	PATL2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PATL2	RGD	RGD:1307887
Canis familiaris	PATL2	VGNC	VGNC:44273
Bos taurus	PATL2	VGNC	VGNC:32594
Mus musculus	PATL2	MGD	MGI:1914828
Macaca mulatta	PATL2	VGNC	VGNC:75708
Felis catus	PATL2	VGNC	VGNC:64050

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