PATL2 - PAT1 homolog 2 Gene

Also Known as OOMD4; Pat1a; hPat1a

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 197135

About PATL2

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:44,665,732-44,711,390 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 179 orthologues, 1 paralogue and is associated with 2 phenotypes. Broad expression in spleen (RPKM 2.6), lymph node (RPKM 2.5) and 20 other tissues.

Summary

Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PATL2 Products (7)

mRNA Protein Name
NM_001145112.2 NP_001138584.1 protein PAT1 homolog 2 isoform 1
NM_001330283.2 NP_001317212.1 protein PAT1 homolog 2 isoform 2
NM_001387260.1 NP_001374189.1 protein PAT1 homolog 2 isoform 3
NM_001387261.1 NP_001374190.1 protein PAT1 homolog 2 isoform 1
NM_001387262.1 NP_001374191.1 protein PAT1 homolog 2 isoform 1
NM_001387263.1 NP_001374192.1 protein PAT1 homolog 2 isoform 1
NM_001387264.1 NP_001374193.1 protein PAT1 homolog 2 isoform 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20584987 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20584987 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PATL2 Protein Structure

PAT1

PAT1: Topoisomerase II-associated protein PAT1 (150 - 227)

PAT1

PAT1: Topoisomerase II-associated protein PAT1 (254 - 490)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 543 a.a.
Protein Preferred Names Protein Names

protein PAT1 homolog 2

  • PAT1-like protein 2

Related Diseases

Diseases Alias
Oocyte Maturation Defect 4

  • OOMD4

  • Oocyte Maturation Defect, Type 4
Female Infertility Due To Oocyte Meiotic Arrest
Oocyte Maturation Defect 2

  • OOMD2

  • Oocyte Maturation Defect, Type 2
Infertility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10085 PATL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PATL2 RGD RGD:1307887
Canis familiaris PATL2 VGNC VGNC:44273
Bos taurus PATL2 VGNC VGNC:32594
Mus musculus PATL2 MGD MGI:1914828
Macaca mulatta PATL2 VGNC VGNC:75708
Felis catus PATL2 VGNC VGNC:64050
Others PATL2 NCBI