Slpi - secretory leukocyte peptidase inhibitor Gene

Also Known as ALP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20568

Summary

Enables endopeptidase inhibitor activity. Involved in Antibacterial humoral response; innate immune response; and response to lipopolysaccharide. Located in extracellular space. Is expressed in embryo; liver left lobe; liver right lobe; and ureter. Orthologous to human SLPI (secretory leukocyte peptidase inhibitor). [provided by Alliance of Genome Resources, Apr 2022]

Slpi Products (4)

mRNA Protein Name
NM_001412601.1 NP_001399530.1 antileukoproteinase isoform 1 precursor
NM_001412602.1 NP_001399531.1 antileukoproteinase isoform 1 precursor
NM_001412603.1 NP_001399532.1 antileukoproteinase isoform 2 precursor
NM_011414.4 NP_035544.1 antileukoproteinase isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
12526812 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12526812 MGI
Biological Process GO Annotation Evidence References Source
involved in antibacterial humoral response IMP
IMP: Inferred from mutant phenotype
18322212 MGI
involved in immune response IMP
IMP: Inferred from mutant phenotype
12615907 MGI
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
18322212 MGI
involved in response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
12615907 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
18322212 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

antileukoproteinase

  • secretory leukocyte protease inhibitor

Recombinant Slpi Proteins

Cat. No. Product Name Accession Purity
HY-P78041 SLPI Protein, Mouse (HEK293, Fc) P97430 (S26-M131) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13382 SLPI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17168 Slpi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23618 Slpi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slpi NCBI NCBI:6590