Sncg - synuclein, gamma Gene

Also Known as persyn

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20618

Summary

Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and cuprous ion binding activity. Involved in protein secretion. Acts upstream of or within several processes, including adult locomotory behavior; chemical synaptic transmission; and regulation of secretion by cell. Located in axon; cytoplasm; and neuronal cell body. Is expressed in adipose tissue; central nervous system; intestine; peripheral nervous system; and retina. Used to study amyotrophic lateral sclerosis type 1. Human ortholog(s) of this gene implicated in Lewy body dementia. Orthologous to human SNCG (synuclein gamma). [provided by Alliance of Genome Resources, Apr 2022]

Sncg Products (1)

mRNA Protein Name
NM_011430.3 NP_035560.1 gamma-synuclein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16392033 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult locomotory behavior IGI
IGI: Inferred from genetic interaction
18333965 MGI
acts upstream of or within chemical synaptic transmission IGI
IGI: Inferred from genetic interaction
20974939 MGI
involved in protein secretion IDA
IDA: Inferred from direct assay
16392033 MGI
acts upstream of or within regulation of dopamine secretion IGI
IGI: Inferred from genetic interaction
18333965 MGI
acts upstream of or within regulation of neurotransmitter secretion IGI
IGI: Inferred from genetic interaction
18333965 MGI
acts upstream of or within synapse organization IGI
IGI: Inferred from genetic interaction
20974939 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
9801372 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
9801372 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
9801372 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-synuclein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10844 ANK peptide / Unkown
HY-RS13487 SNCG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19382 Sncg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25874 Sncg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99828 Cofetuzumab 99.31% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sncg NCBI NCBI:6623