Trim21 - tripartite motif-containing 21 Gene

Also Known as Ro52; Ssa1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20821

Summary

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein Ligase activity. Involved in positive regulation of viral entry into host cell. Located in cytoplasm. Is expressed in central nervous system; genitourinary system; retina; and thymus primordium. Orthologous to human TRIM21 (tripartite motif containing 21). [provided by Alliance of Genome Resources, Apr 2022]

Trim21 Products (2)

mRNA Protein Name
NM_001082552.2 NP_001076021.1 E3 ubiquitin-protein ligase TRIM21
NM_009277.4 NP_033303.3 E3 ubiquitin-protein ligase TRIM21

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23222971 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11331580 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM21

  • 52 kDa Ro protein

  • 52 kDa ribonucleoprotein autoantigen Ro/SS-A

  • 52kD Ro/SSA autoantigen

  • RING-type E3 ubiquitin transferase TRIM21

  • SS-A

  • Sjogren syndrome antigen A1

  • ro(SS-A)

  • sjoegren syndrome type A antigen

  • tripartite motif protein 21

  • tripartite mot

Recombinant Trim21 Proteins

Cat. No. Product Name Accession Purity
HY-P71570 TRIM21 Protein, Mouse (His-SUMO) Q62191 (M1-M470) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-169356 Acepromazine-OTs / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim21 NCBI NCBI:6737