Stac - src homology three (SH3) and cysteine rich domain Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20840

Summary

Enables transmembrane transporter binding activity. Involved in positive regulation of protein localization to plasma membrane and positive regulation of voltage-gated Calcium Channel activity. Acts upstream of or within cellular response to heat; muscle contraction; and regulation of voltage-gated Calcium Channel activity. Located in T-tubule. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed in lens. Orthologous to human STAC (SH3 and cysteine rich domain). [provided by Alliance of Genome Resources, Apr 2022]

Stac Products (2)

mRNA Protein Name
NM_001324546.1 NP_001311475.1 SH3 and cysteine-rich domain-containing protein isoform 2
NM_016853.3 NP_058549.1 SH3 and cysteine-rich domain-containing protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
27149520 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to heat IDA
IDA: Inferred from direct assay
18755693 MGI
acts upstream of or within muscle contraction IMP
IMP: Inferred from mutant phenotype
23818578 MGI
involved in positive regulation of cation channel activity IMP
IMP: Inferred from mutant phenotype
27149520 MGI
involved in positive regulation of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
27149520 MGI
involved in positive regulation of voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
29467163 MGI
acts upstream of or within regulation of voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
23818578 MGI
Cellular Component GO Annotation Evidence References Source
located in T-tubule IDA
IDA: Inferred from direct assay
23818578 MGI
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
29467163 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 and cysteine-rich domain-containing protein

  • SRC homology 3 and cysteine-rich domain-containing protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16558 Butein 99.64% Unkown
HY-114981 SRTCX1002 Activator / Unkown
HY-RS13863 STAC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13864 STAC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13865 STAC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17897 Stac Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24366 Stac Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stac NCBI NCBI:6769