Stc2 - stanniocalcin 2 Gene
Also Known as Stc-2; Stc2l; mustc2
Species: Mus musculus
Summary
Predicted to enable enzyme binding activity; heme binding activity; and protein homodimerization activity. Acts upstream of or within several processes, including cellular calcium ion homeostasis; endoplasmic reticulum unfolded protein response; and regulation of store-operated calcium entry. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; olfactory epithelium; and vertebral axis musculature. Orthologous to human STC2 (stanniocalcin 2). [provided by Alliance of Genome Resources, Apr 2022]
Stc2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_011491.3 | NP_035621.1 | stanniocalcin-2 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21746875 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within calcium ion homeostasis |
IGI
IGI: Inferred from genetic interaction
|
22285620 | MGI |
| acts upstream of or within endoplasmic reticulum unfolded protein response |
IMP
IMP: Inferred from mutant phenotype
|
15485913 | MGI |
| acts upstream of or within intracellular calcium ion homeostasis |
IMP
IMP: Inferred from mutant phenotype
|
21746875 | MGI |
| acts upstream of or within negative regulation of multicellular organism growth |
IMP
IMP: Inferred from mutant phenotype
|
18258678 | MGI |
| acts upstream of or within regulation of store-operated calcium entry |
IMP
IMP: Inferred from mutant phenotype
|
21746875 | MGI |
| acts upstream of or within response to endoplasmic reticulum stress |
IMP
IMP: Inferred from mutant phenotype
|
21746875 | MGI |
| acts upstream of or within response to oxidative stress |
IMP
IMP: Inferred from mutant phenotype
|
21746875 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in Golgi apparatus |
IDA
IDA: Inferred from direct assay
|
15485913 | MGI |
| located in endoplasmic reticulum |
IDA
IDA: Inferred from direct assay
|
15485913 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
stanniocalcin-2 |
|
Recombinant Stc2 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71450 | STC2/Stanniocalcin-2 Protein, Mouse | O88452 (T25-R296) | ≥ 90%, as determined by reducing SDS-PAGE. |