Il31ra - interleukin 31 receptor A Gene
Also Known as GPL; CRL3; Glmr; NR10; GLM-R
Species: Mus musculus
Summary
Enables cytokine binding activity. Acts upstream of or within acute inflammatory response to antigenic stimulus; defense response to Other organism; and glandular epithelial cell differentiation. Located in external side of plasma membrane. Is expressed in brain; peripheral nervous system; reproductive system; and stomach. Human ortholog(s) of this gene implicated in primary localized cutaneous amyloidosis 2. Orthologous to human IL31RA (interleukin 31 receptor A). [provided by Alliance of Genome Resources, Apr 2022]
Il31ra Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_139299.2 | NP_647460.2 | interleukin-31 receptor subunit alpha precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables cytokine binding |
IPI
IPI: Inferred from physical interaction
|
21182835 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within T-helper 2 cell cytokine production |
IMP
IMP: Inferred from mutant phenotype
|
19414760 | MGI |
| acts upstream of or within acute inflammatory response to antigenic stimulus |
IMP
IMP: Inferred from mutant phenotype
|
19414760 | MGI |
| acts upstream of or within defense response to other organism |
IMP
IMP: Inferred from mutant phenotype
|
19414760 | MGI |
| acts upstream of or within glandular epithelial cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
19414760 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in external side of plasma membrane |
IDA
IDA: Inferred from direct assay
|
21182835 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
interleukin-31 receptor subunit alpha |
|
|
Recombinant Il31ra Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P77968 | IL-31R alpha Protein, Mouse (HEK293, His) | Q8K5B1-1 (V19-T499) | ≥ 95%, as determined by Bis-Tris PAGE. |