LRRC55 - leucine rich repeat containing 55 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 219527

About LRRC55

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,181,953-57,191,717 (from NCBI)

This gene has 2 transcripts (splice variants), 119 orthologues and 25 paralogues. Broad expression in brain (RPKM 2.8), lymph node (RPKM 1.5) and 14 other tissues.

Summary

Enables Potassium Channel activator activity; transmembrane transporter binding activity; and voltage-gated Potassium Channel activity. Involved in positive regulation of voltage-gated Potassium Channel activity and potassium ion transmembrane transport. Part of voltage-gated Potassium Channel complex. [provided by Alliance of Genome Resources, Apr 2022]

LRRC55 Products (1)

mRNA Protein Name
NM_001005210.4 NP_001005210.2 leucine-rich repeat-containing protein 55 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables potassium channel activator activity IDA
IDA: Inferred from direct assay
22547800 GOA
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
22547800 GOA
enables voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
22547800 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
22547800 GOA
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
22547800 GOA
Cellular Component GO Annotation Evidence References Source
part of voltage-gated potassium channel complex IDA
IDA: Inferred from direct assay
22547800 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC55 Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (81 - 107)

(111 - 124)

LRR_8

LRR_8: Leucine rich repeat (133 - 190)

  • 0
  • 100
  • 200
  • 300
  • 341 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 55

  • BK channel auxiliary gamma subunit LRRC55

Related Diseases

Diseases Alias
Lymph Node Carcinoma

  • Lymph Node Cancer

  • Lymph Node Neoplasm

  • Neoplasm Of Lymph Node
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07823 LRRC55 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LRRC55 VGNC VGNC:82022
Macaca mulatta LRRC55 VGNC VGNC:107455
Mus musculus LRRC55 MGD MGI:2685197
Canis familiaris LRRC55 VGNC VGNC:42805
Bos taurus LRRC55 VGNC VGNC:31022
Rattus norvegicus LRRC55 RGD RGD:1561726
Others LRRC55 NCBI