Tpi1 - triosephosphate isomerase 1 Gene

Also Known as TIM; Tpi; Tpi-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21991

Summary

Enables triose-phosphate isomerase activity. Involved in glyceraldehyde-3-phosphate metabolic process. Acts upstream of or within glucose metabolic process. Predicted to be located in nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study triosephosphate isomerase deficiency. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tpi1 Products (1)

mRNA Protein Name
NM_009415.3 NP_033441.3 triosephosphate isomerase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables isomerase activity IDA
IDA: Inferred from direct assay
566475 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25707359 MGI
enables triose-phosphate isomerase activity IDA
IDA: Inferred from direct assay
176725 MGI
enables triose-phosphate isomerase activity IMP
IMP: Inferred from mutant phenotype
3796661 MGI
Biological Process GO Annotation Evidence References Source
involved in canonical glycolysis IGI
IGI: Inferred from genetic interaction
30174313 MGI
acts upstream of or within embryo development IMP
IMP: Inferred from mutant phenotype
2693209 MGI
involved in gluconeogenesis IDA
IDA: Inferred from direct assay
31891762 MGI
acts upstream of or within glucose metabolic process IDA
IDA: Inferred from direct assay
2693209 MGI
involved in glyceraldehyde-3-phosphate metabolic process IDA
IDA: Inferred from direct assay
15155459 MGI
acts upstream of or within multicellular organism development IMP
IMP: Inferred from mutant phenotype
3796661 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
12581871 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

triosephosphate isomerase

  • methylglyoxal synthase

  • triose-phosphate isomerase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100463 TPI-1 Inhibitor 98.0% Unkown
HY-RS14934 TPI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17377 Tpi1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23831 Tpi1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpi1 NCBI NCBI:7167