Tpt1 - tumor protein, translationally-controlled 1 Gene

Also Known as Trt; p21; p23; TCTP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22070

Summary

Predicted to enable calcium ion binding activity. Involved in negative regulation of ectoderm development and stem cell population maintenance. Located in nucleoplasm. Is expressed in sciatic nerve and testis. Orthologous to several human genes including TPT1 (tumor protein, translationally-controlled 1). [provided by Alliance of Genome Resources, Apr 2022]

Tpt1 Products (1)

mRNA Protein Name
NM_009429.3 NP_033455.1 translationally-controlled tumor protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
21076177 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21048921 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ectoderm development IMP
IMP: Inferred from mutant phenotype
21076177 MGI
involved in stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
21076177 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleoplasm IDA
IDA: Inferred from direct assay
21076177 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

translationally-controlled tumor protein

  • 21 kDa polypeptide under translational control

  • fortilin

  • translationally regulated transcript (21 kDa)

Tpt1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tpt1 P63028 Ncl Mus musculus P09405
Pull Down
21048921
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10293 PDSS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14956 TPT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18795 Tpt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22714 Pdss1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25284 Tpt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpt1 NCBI NCBI:7178