Soat2 - sterol O-acyltransferase 2 Gene

Also Known as ACAT2; D15Wsu97e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223920

Summary

Enables sterol O-acyltransferase activity. Acts upstream of or within Cholesterol metabolic process. Located in membrane. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Soat2 Products (1)

mRNA Protein Name
NM_146064.1 NP_666176.1 sterol O-acyltransferase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sterol O-acyltransferase activity IDA
IDA: Inferred from direct assay
9756919 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cholesterol metabolic process IDA
IDA: Inferred from direct assay
9756919 MGI
acts upstream of or within cholesterol storage IGI
IGI: Inferred from genetic interaction
25450374 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
9756919 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sterol O-acyltransferase 2

  • ACAT-2

  • acyl-CoA:cholesterol acyltransferase

  • acyl-coenzyme A:cholesterol acyltransferase 2

  • cholesterol acyltransferase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117832 Pyripyropene A Inhibitor 99.37% Unkown
HY-RS13550 SOAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19037 Soat2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25526 Soat2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Soat2 NCBI NCBI:8435