2. Gene
  3. Xdh - xanthine dehydrogenase Gene

Xdh - xanthine dehydrogenase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as XO; Xor; Xox1; Xox-1

Gene ID: 22436 | Gene type: protein coding

About Xdh

Chromosome 17: 74,190,890-74,257,191 reverse strand.GRCm39:CM001010.3

This gene has 14 transcripts (splice variants), 208 orthologues, 4 paralogues and is associated with 41 phenotypes. Broad expression in duodenum adult (RPKM 55.7), small intestine adult (RPKM 47.7) and 16 other tissues.

Summary

This gene encodes a member of the xanthine dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein exists as two distinct enzymatic forms, either as xanthine dehydrogenase, or as Xanthine Oxidase, and functions in purine degradation. Additional studies also suggest a role in adipogenesis, and a function as a structural protein in milk fat droplets in the lactating mammary gland. [provided by RefSeq, Jan 2014]

Xdh Products(1)

mRNA Protein Name
NM_011723.3 NP_035853.2 xanthine dehydrogenase/oxidase

Xdh Protein Structure

PLN02906

PLN02906: cl33596 (25 - 1320)

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  • 1335 a.a.
Protein Preferred Names Protein Names

xanthine dehydrogenase/oxidase

xanthine oxidase

xanthine oxidoreductase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15869 XDH Human Pre-designed siRNA Set A / Unkown
HY-RS15870 Xdh Mouse Pre-designed siRNA Set A / Unkown
HY-RS15871 Xdh Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xdh NCBI NCBI:7498