Kcnt1 - potassium channel, subfamily T, member 1 Gene

Also Known as slo2; Slack; Slo2.2; C030030G16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227632

Summary

This gene encodes a member of the Slo Potassium Channel family that has shown to be activated by both sodium and chloride ions. This channel represents the largest Potassium Channel subunit yet identified. This channel may be important in development and pain signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Kcnt1 Products (3)

mRNA Protein Name
NM_001145403.3 NP_001138875.1 potassium channel subfamily T member 1 isoform 2
NM_001302351.2 NP_001289280.1 potassium channel subfamily T member 1 isoform 3
NM_175462.5 NP_780671.2 potassium channel subfamily T member 1 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
34664085 MGI
involved in regulation of postsynaptic membrane potential IEP
IEP: Inferred from expression pattern
34664085 MGI
involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
34664085 MGI
Cellular Component GO Annotation Evidence References Source
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
34664085 MGI
is active in postsynaptic density membrane IEP
IEP: Inferred from expression pattern
34664085 MGI
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
34664085 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily T member 1

  • potassium channel subunit homolog

  • sodium-activated potassium channel

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162549 CPK20 Inhibitor 99.67% Unkown
HY-159958 KNa1.1-IN-2 Antagonist / Unkown
HY-175335 KCNT1-IN-1 Inhibitor 99.18% Unkown
HY-179093 KCNT1-IN-3 Inhibitor / Unkown
HY-RS07181 KCNT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175336 KCNT1-IN-2 Inhibitor / Unkown
HY-P0058S Pramlintide-(Ala-13C3,15N) / Unkown
HY-RS22590 Kcnt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnt1 NCBI NCBI:57582